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US 9,745,331 B2Granted
Therapeutic bisphosphonates
AssigneeUniversity of Iowa Research Foundation
InventorDavid Wiemer
Life of this patent
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Abstract
The invention provides novel pyrophosphate synthase inhibitors of formula I and formula II as well salts thereof; the invention also provides compositions comprising such inhibitors and methods for their use.
Claims4
A compound of formula I:
- wherein:
- X is —(CH2)m— or —(CH2)mCH(CH3)—
- m is an integer from 1 to 2;
- R1 is a saturated or unsaturated (C1-C20)alkyl chain;
- R2 is H or methyl;
- each R3, R4, R5, and R6 is independently OH, or (C1-C6)alkoxy;
- R7 is
- or a salt thereof.
5 more elements
Dependencies are inferred from the claim text.