Nicotine salts, co-crystals, and salt co-crystal complexes
AssigneeR.J. Reynolds Tobacco Company
InventorsGary M. Dull, Andrew Carr, Emma Sharp
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AssigneeR.J. Reynolds Tobacco Company
InventorsGary M. Dull, Andrew Carr, Emma Sharp
Estimating the term…
The invention provides certain nicotine salts, co-crystals, and salt co-crystals and provides novel polymorphic forms of certain nicotine salts. In particular, nicotine salts with mucic acid, 3,5-dihydroxybenzoic acid, and 2,3-dihydroxybenzoic acid, and crystalline polymorphic forms of nicotine 4-acetamidobenzoate, nicotine gentisate, and nicotine 1-hydroxy-2-naphthoate are described. The invention further provides methods of preparation and characterization of such nicotine salts, co-crystals, and salt co-crystals and polymorphic forms thereof. In addition, tobacco products, including smoking articles, smokeless tobacco products, and electronic smoking articles comprising nicotine salts, co-crystals, and/or salt co-crystals are also provided.
A salt of nicotine and mucic acid, characterized by an X-ray powder diffraction pattern having peaks at one or more of the following 2-theta diffraction angles:
Dependencies are inferred from the claim text.