Systems, methods, and apparatuses for securing cell-based products for transport in thermal isolation

A system configured for thermally isolating biologic products for transport, the system comprising:

• a containment apparatus configured to secure one or more containers for biologic products for transport, the containment apparatus comprising:
• a first component comprising one or more sidewalls, the one or more sidewalls forming an enclosed volume of the first component, the enclosed volume being fluidly sealed from an environment surrounding the first component, the first component further comprising:
• one or more recessed wells, individual ones of the one or more recessed wells being configured to receive at least part of individual ones of the one or more containers, the individual ones of the one or more recessed wells including:
• an open end,
• a closed end opposite the open end, and
• wherein the closed end extends into the enclosed volume of the first component;
• a second component comprising one or more second sidewalls, the one or more second sidewalls forming a second enclosed volume of the second component, the second enclosed volume being fluidly sealed from an environment surrounding the second component, the second component further comprising;
• one or more second recessed wells, individual ones of the one or more second recessed wells being configured to receive at least part of the individual ones of the one or more containers, the individual ones of the one or more second recessed wells including:
• a second open end,
• a second closed end opposite the second open end, and
• wherein the second closed end extends into the second enclosed volume of the second component;
• wherein the first component and second component are configured to cooperatively engage in a closed position of the containment apparatus, the closed position facilitating a securement of the one or more containers by the containment apparatus;
• wherein individual ones of the enclosed volume and second enclosed volume are at least partially filled with a cooling media;
• and
• wherein at least part of the individual ones of the one or more recessed wells come into contact with the cooling media in the enclosed volume to facilitate heat transfer between the cooling media and the individual ones of the one or more containers disposed in the individual ones of the one or more recessed wells during securement of the one or more containers by the containment apparatus;
• a sleeve, the sleeve being configured to at least partially encompass the containment apparatus when in the closed position, the sleeve comprising one or more insulated sidewalls, individual ones of the one or more insulated sidewalls having an outer layer and an inner layer forming a third enclosed volume between the inner and outer layers, the third enclosed volume being fluidly sealed from an environment surrounding the sleeve;
• and
• wherein the second enclosed volume is at least partially filled with the cooling media.

A method of securing biologic products for transport in thermal isolation, the method being implemented using a containment apparatus configured to secure one or more containers for biologic products for transport, wherein the containment apparatus comprises a first component and a second component configured to cooperatively engage in a closed position of the containment apparatus, the closed position facilitating a securement of the one or more containers by the containment apparatus, wherein the first component comprises one or more sidewalls forming an enclosed volume of the first component, the enclosed volume being fluidly sealed from an environment surrounding the first component and at least partially filled with cooling media, the first component further comprising one or more recessed wells that are configured to receive at least part of individual ones of the one or more containers, and wherein the second component comprises one or more second sidewalls forming a second enclosed volume of the second component, the second enclosed volume being fluidly sealed from an environment surrounding the second component and at least partially filled with the cooling media, wherein at least part of individual ones of the one or more recessed wells come into contact with the cooling media within the enclosed volume to facilitate heat transfer between the cooling media and the individual ones of the one or more containers disposed in the individual ones of the one or more recessed wells during securement of the one or more containers by the containment apparatus, the method comprising:

• cooling the first component and second component to a first temperature such that the cooling media disposed within the enclosed volume and second enclosed volume is in a first phase at the first temperature;
• positioning the individual ones of the one or more containers within the individual ones of the one or more recessed wells of the first component;
• and
• engaging the second component to the first component in the closed position of the containment apparatus to facilitate the securement of the one or more containers within the containment apparatus.