Method and composition of inducing hair follicle neogenesis
AssigneesNational Taiwan University, Academia Sinica
InventorsSung-Jan Lin, Mai-Yi Fan, Yu-Ju Chen, Chia-Feng Tsai
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Abstract
The present invention provides a method of inducing hair follicle neogenesis in the skin of a subject in need by transplanting the mixture of the skin extract or the composition with epidermal cells or fibroblasts into the subject. The skin extract of the present invention is obtained by mincing and mixing a skin tissue with phosphate buffer solution, thawing the skin tissue after freeze. The composition of the present invention includes at least lumican, galectin-1 and apolipoprotein A-I.
Claims10
A method of inducing hair follicle neogenesis in the skin of a subject in need thereof, comprising the steps of:
- a. providing a skin extract, wherein the skin extract is obtained from mincing and mixing a skin tissue derived from the subject with phosphate buffer solution (PBS) to form a skin tissue solution, thawing the skin tissue solution after overnight freeze;
- b. mixing the skin extract with a cell to form a mixture, wherein the cell is a epithelial cell or a fibroblast derived from the subject;
- and
- c. transplanting the mixture into the subject.
Dependencies are inferred from the claim text.