Back to results
US 9,725,431 B2Granted
Oligomer-tricyclic conjugates
AssigneeNektar Therapeutics
InventorsWen Zhang, Xuyuan Gu, Stephanie Allums-Donald, Jennifer Riggs-Sauthier
Life of this patent
Estimating the term…
Abstract
The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water-soluble oligomer.
Claims11
A method of treatment, comprising administering a stable conjugate selected from:
- wherein n is an integer from 1 to 30, to a patient in need thereof;
- wherein the compound is administered for sedative, hypnotic, anti-anxiety, tranquilizing, anti convulsant, muscle relaxant, anti-depressant, or analgesic effect.
Dependencies are inferred from the claim text.