Electrophoresis gel cassette and comb

An apparatus for gel electrophoresis comprising:

• a gel cassette, said gel cassette being configured to accommodate an electrophoresis gel, wherein the gel cassette comprises a retainer plate and a divider plate and a lip extends from the exterior surface of the divider plate or the retainer plate;
• and
• a comb having at least one wedge-shaped tooth, the wedge-shaped tooth having a first thickness at the proximal end of the tooth and a second thickness at the distal end of the tooth, said first thickness being greater than said second thickness, wherein the comb comprises a recessed area on the comb, wherein the recessed area is configured to prevent the formation of a skin during gel formation
• wherein an angled surface of the wedge-shaped tooth extends at an angle from the distal end to the proximal end of the tooth thereby defining a wedge shape,
• wherein said at least one wedge-shaped tooth is configured to form a wedge-shaped sample well in said electrophoresis gel such that when said comb is removed, a void formed by said wedge-shaped tooth defines a sample well in said electrophoresis gel.