US 9,707,551 B2 · Reaction catalyst for cross-coupling and method for manufacturing aromatic compound

Abstract

The object of the present invention is to provide a new organic phosphorus ligand that can efficiently promote cross-coupling reaction to obtain the target substance at high yield, as well as a method of manufacturing such ligand whose steric characteristics and electronic characteristics can be fine-tuned and which can be used to cause cross-coupling reaction at high yield. As a means for achieving the aforementioned object, a phosphine compound expressed by General Formula (1) below is provided. (In the formula, R1 and R2 are each independently a secondary alkyl group, tertiary alkyl group, or cycloalkyl group, while R3 and R4 are each independently a hydrogen, aliphatic group, heteroaliphatic group, aromatic group, alicyclic group, or heterocyclic group. Note that R3 and R4 have no phosphorus atom and that R3 and R4 are not both hydrogen at the same time).

Claims6

Dependent claims

A phosphine compound expressed by General Formula (1) below:

(In the formula, R1 and R2 are each independently a secondary alkyl group, tertiary alkyl group, or cycloalkyl group, while R3 and R4 are each independently a hydrogen, aliphatic group, aromatic group, alicyclic group, or heterocyclic group;
note that R3 and R4 have no phosphorus atom and that R3 and R4 are not both hydrogen at the same time).

Dependencies are inferred from the claim text.

Facts

Application

14/762,456Filed 23 Jan 2014

Priority

JP 2013-01055223 Jan 2013

Published

US 2015/0360214 A117 Dec 2015

Granted

18 Jul 2017

Term ends

Not estimatedThe source records don’t support an estimate.

Classification17 codes

B01J 31/24
Containing coordination complexes: phosphines , i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g.…
C07C 1/321
Starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen: the hetero-atom being a non-metal atom
C07C 41/30
By reactions not forming ether-oxygen bonds: by increasing the number of carbon atoms, e.g. by oligomerisation
C07C 209/10
By substitution of halogen atoms: with formation of amino groups bound to carbon atoms of six-membered aromatic rings or from amines having…

Reaction catalyst for cross-coupling and method for manufacturing aromatic compound

Life of this patent

Reaction catalyst for cross-coupling and method for manufacturing aromatic compound

Life of this patent

Abstract

Claims6