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US 9,706,951 B2Granted
Methods for assessing vaginal atrophy
AssigneeThe Procter & Gamble Company
InventorsRaphael Warren, Dean Larry DuVal, Miranda Aref Farage, Charles Carson Bascom, Gina Marie Fadayel, Kenneth Robert Wehmeyer, Jay Patrick Tiesman, David Burton Moore, Murray A. Friedman
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Abstract
An array of methods for assessing vaginal atrophy are disclosed. The methods may be used alone or in combination with a treatment or as part of a kit.
Claims12
A method for identifying urogenital changes associated with vaginal atrophy, the method comprising:
- a. measuring pH at the labia majora, labia minora, introitus, or combinations thereof;
- b. determining brush sensitivity at the introitus;
- c. assessing glycogen amount at the introitus;
- d. analyzing epithelial cells sampled at the introitus;
- e. assessing protein amount at the introitus or the labia majora or the labia minora;
- f. assessing metabolites amounts at the introitus or the labia majora or the labia minora;
- g. assessing histamine amount at the introitus or the labia majora or the labia minora;
- h. transcriptomic heat mapping at the labia majora or the labia minora or the introitus;
- and
- i. evaluating gene expression at the labia majora using a gene probe set.
7 more elements
Dependencies are inferred from the claim text.