Integrated zwitterionic conjugated polymers for bioelectronics, biosensing, regenerative medicine, and energy applications
AssigneeThe University of Akron
InventorGang Cheng
Life of this patent
Estimating the term…
Loading patent…
AssigneeThe University of Akron
InventorGang Cheng
Estimating the term…
The present invention is directed to a versatile and high performance zwitterionic CP platform, which integrates all desired functions into one material. This zwitterionic CP consists of the conducting backbone and multifunctional zwitterionic side chains. Non-conducting zwitterionic materials gain electronic conductivity through the conducting backbone and CPs obtain excellent biocompatibility, sensitivity to environmental stimuli and controllable antifouling properties via multifunctional zwitterionic side chains. Unique properties from two distinct materials (conducting materials and zwitterionic materials) are integrated into one material without sacrificing any properties. This platform can potentially be adapted for a range of applications (e.g. bioelectronics, tissue engineering, wound healing, robotic prostheses, biofuel cell, etc.), which all require high performance conducting materials with excellent antifouling/biocompatibility at complex biointerfaces. This conducting material platform will significantly advance the development of conducting polymers in the field of biomedicine and biotechnology.
A conjugated polymer platform for use with bioelectronics, biosensing, regenerative medicine, or energy applications comprising a conjugated polymer backbone having one or more zwitterionic side chains and one or more other side chains selected from the group consisting of crosslinking side chains, side chains for securing said conjugated polymer platform to a surface, redox sensitive side chains, both positively and negatively charged side chains, and combinations thereof, wherein said zwitterionic side chains further comprise a carboxybetaine group, a sulfobetaine group, a phosphobetaine group or combinations thereof.
Dependencies are inferred from the claim text.