Methods of treating an overweight or obese subject
AssigneeZafgen, Inc.
InventorJames E. Vath
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Abstract
The disclosure herein generally relates to methods of treating an overweight or obese condition, and overweight or obesity-related conditions. In one embodiment, the disclosure provides a method of treating an overweight or obese condition involving administering to the subject in need thereof, an amount of a pharmaceutical composition including a MetAp-2 inhibitory compound, or a salt, ester, or prodrug thereof, effective to result in weight loss in the subject.
Claims7
A method of treating a subject having an overweight or obese condition, the method comprising:
- administering to the subject in need thereof, a therapeutically effective amount of a pharmaceutical composition comprising a compound of Formula C-D wherein C is represented by:
- and D is represented by:
- wherein:
- Z, R and Y are not present;
- X is C1-6alkyl;
- P is a moiety selected from the group consisting of:
- or a pharmaceutically acceptable salt thereof.
A method of treating a subject having an overweight or obese condition, the method comprising:
- administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising a compound selected from the group consisting of:
- and a pharmaceutically acceptable salt thereof.
A method for controlling hepatic steatosis in an obese subject being treated for obesity, comprising administering a therapeutically effective amount of a pharmaceutical composition comprising a compound selected from the group consisting of:
- and a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.