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US 9,637,729 B2Granted
Cell and enzyme compositions for modulating bile acids, cholesterol and triglycerides
AssigneeUAS Laboratories LLC
InventorsSatya Prakash, Mitchell Lawrence Jones
Life of this patent
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Abstract
The invention relates to immobilized or encapsulated enzyme and/or cells to lower bile acids and cholesterol. The invention also relates to methods of quantitatively measuring bile acids. The invention provides a composition for decreasing the amount of a target compound in the gastrointestinal tract of an animal, comprising: a) a biologically active agent which decreases the amount of the target compound; b) a retainer for retaining the biologically active agent by contacting the agent to limit movement of the agent; and c) a carrier.
Claims32
A composition comprising:
- a. a bile-permeable microcapsule comprising a cell-free bile acid deconjugating enzyme in an amount sufficient to deconjugate bile in said microcapsule in a small intestine;
- and
- b. a carrier;
- wherein said bile-permeable microcapsule permits entry of said bile and retains at least a portion of a bile acid precipitate produced from said bile by said bile acid deconjugating enzyme.
1 more element
Dependencies are inferred from the claim text.