Therapeutic use of neural stem cells
AssigneeReneuron Limited
InventorsRandolph Corteling, Caroline Hicks, John Sinden, Jack Price
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Abstract
The present invention provides an isolated cell obtainable from the CTX0E03 neural stem cell line for use in the treatment of a disorder associated with elevated levels of pro-inflammatory cytokines, wherein the disorder is selected from unipolar and bipolar depression, schizophrenia, obsessive compulsive disorder, autism and autistic syndrome disorders.
Claims3
A method for treating a patient having unipolar or bipolar depression, wherein said method comprises administering to the patient a composition comprising a cell obtainable from the CTX0E03 neural stem cell line.
A method for treating a patient having unipolar or bipolar depression, wherein said method comprises administering to the patient a composition comprising a cell obtainable from the CTX0E03 neural stem cell line, wherein the patient has an elevated level, systemically or in the brain, of one or more pro-inflammatory cytokines at the time of said administering, and wherein the cell expresses Programmed Death Ligand-1 (PDL-1) in the patient.
Dependencies are inferred from the claim text.