US 9,626,587 B2 · Iterative reconstruction scheme for phase contrast tomography

Abstract

A method of tomographic imaging the real part of the refractive index of the internal structure of an image volume and a corresponding apparatus for performing the method. The method includes a two-step process of first retrieving phase projections of an image volume from projective intensity measurements through the image volume. The second step of the method includes iterative image reconstruction of an image of the image volume using phase projections taken at multiple projection angles. The first step of intensity measurements and subsequent phase retrieval can use one of many possible phase retrieval methods including the Bronnikov phase retrieval method. The second step of iterative image reconstruction can be performed using the total variation minimization method, the algebraic reconstruction technique method, or any other iterative image reconstruction method.

Claims11

Dependent claims

A method of computer aided imaging, comprising:

obtaining intensity data representing an intensity of radiation at a detector array, wherein a first dataset of the intensity data represents the intensity of the radiation at the detector array after propagating a first distance past an exit plane of an image volume, a second dataset of the intensity data represents the intensity of the radiation at the detector array after propagating a second distance past the exit plane of the image volume, and the first distance is greater than the second distance;
determining, using a phase retrieval method and the intensity data, a phase of the radiation at the exit plane of the image volume;
and
reconstructing an image of a real part of an index of refraction of the image volume using an iterative reconstruction algorithm, including performing an affine projection of an image vector onto an affine space determined by a plurality of Radon transforms corresponding to the intensity data, and the image vector represents the real part of the index of refraction of the image volume.

1 more element

An apparatus for determining an image, comprising:

a processing circuit configured to
obtain intensity data representing an intensity of radiation at a detector array, wherein a first dataset of the intensity data represents the intensity of the radiation at the detector array after propagating a first distance past an exit plane of an image volume, a second dataset of the intensity data represents the intensity of the radiation at the detector array after propagating a second distance past the exit plane of the image volume, and the first distance is greater than the second distance;
determine, using a phase retrieval method and the intensity data, a phase of the radiation at the exit plane of the image volume;
and
reconstruct an image of a real part of an index of refraction of the image volume using an iterative reconstruction algorithm, including performing an affine projection of an image vector onto an affine space determined by a plurality of Radon transforms corresponding to the intensity data, and the image vector represents the real part of the index of refraction of the image volume.

2 more elements

Dependencies are inferred from the claim text.

Iterative reconstruction scheme for phase contrast tomography

Life of this patent

Iterative reconstruction scheme for phase contrast tomography

Life of this patent

Abstract

Claims11