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US 9,624,531 B2Granted
Cassette for sample preparation
AssigneeLuminex Corporation
InventorsJesus Ching, David Hsiang Hu, Steve Jia Chang Yu, Phillip You Fai Lee
Life of this patent
Estimating the term…
Abstract
Apparatuses for preparing a sample are disclosed herein. The apparatuses include a chamber, a first valve at least partially disposed in the first chamber, a second valve at least partially disposed in the first chamber, and a pump comprising an actuator and nozzle.
Claims15
A system comprising:
- a plurality of cassettes, each cassette of the plurality of cassettes comprising:
- a first chamber comprising an opening configured for receiving a sample into the first chamber, and a removable lid configured to provide access to the opening;
- a second chamber;
- a third chamber;
- a first valve comprising a valve housing defining a first valve opening in fluid communication with the first chamber and a second valve opening in fluid communication with the second chamber;
- a second valve comprising a valve housing defining a first valve opening in fluid communication with the second chamber and a second valve opening in fluid communication with the third chamber;
- and
- a plurality of reagent chambers, wherein each of the plurality of reagent chambers comprises a puncturable or sealable member defining at least a portion of a boundary between the plurality of reagent chambers and the first chamber;
- and
- a magazine configured to receive the plurality of cassettes.
7 more elements
A system for preparing a plurality of samples of cells, the system comprising:
- a plurality of cassettes, each cassette of the plurality of cassettes comprising:
- a mixing chamber comprising an opening configured for receiving a sample of cells into the mixing chamber, and a removable lid configured to provide access to the opening;
- a first washing chamber;
- a first valve comprising a valve housing defining a first, valve opening in fluid communication with the mixing chamber and a second valve opening in fluid communication with the first washing chamber;
- a second valve comprising a valve housing defining a first valve opening in fluid communication with the first washing chamber and a second valve opening in fluid communication with a second washing chamber or an elution chamber;
- and
- a plurality of reagent chambers, wherein each of the plurality of reagent chambers comprises a puncturable or sealable member defining at least a portion of a boundary between the plurality of reagent chambers and the mixing chamber, wherein the plurality of reagent chambers contain one or more of a lysis buffer, enzyme, magnetic particles, or chaotropic salt;
- and
- a magazine configured to receive the plurality of cassettes.
6 more elements
Dependencies are inferred from the claim text.