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US 9,623,058 B2Granted
Bacteriophages
AssigneeAmpliphi Biosciences Corporation
InventorYing Jia
Life of this patent
Estimating the term…
Abstract
The present invention provides a bacteriophage with effective antibacterial activity against Staphylococcus strains and in particular MRSA. There is also provided a pharmaceutical composition comprising said bacteriophage and a method of treating a bacterial infection using a composition comprising said bacteriophage.
Claims18
A Staphylococcus bacteriophage K mutant, which comprises one or more mutations within one or more of the following regions, corresponding to the nucleotide sequence of wild-type Staphylococcus bacteriophage K, selected from:
- a) the region between ORF 18 and ORF 19;
- and/or
- b) the region between ORF 41 and ORF 42;
- and/or
- c) ORF 68;
- and/or
- d) an overlapping region within ORF 86/88/90;
- and/or
- e) ORF 92;
- and/or
- f) ORF 93;
- and/or
- g) ORF 96;
- and/or
- h) ORF 100.
12 more elements
Dependencies are inferred from the claim text.