US 9,622,988 B2Granted

Small molecule xanthine oxidase inhibitors and methods of use

AssigneeBaylor College of Medicine

InventorsChangyi Chen, Jian-Ming Lu, Qizhi Yao

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Abstract

Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia.

Claims1

Dependent claims

A method of inhibiting xanthine oxidase activity in a cell comprising contacting said cell with an effective amount of a compound selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

Dependencies are inferred from the claim text.

Facts

Application: 14/483,080Filed 10 Sep 2014 · continuation
Priority: 7 Dec 2012
Published: US 2015/0004699 A11 Jan 2015
Granted: 18 Apr 2017
Term ends: Not estimatedThe source records don’t support an estimate.

Classification17 codes

A61K 31/11
Medicinal preparations containing organic active ingredients: aldehydes
A61K 9/0053
Galenical forms characterised by the site of application: mouth and digestive tract, i.e. intraoral and peroral administration
A61K 31/185
Medicinal preparations containing organic active ingredients: acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic…
A61K 31/277
Nitriles; Isonitriles: having a ring, e.g. verapamil

Family

Application61/734,409Us provisional application · filed 7 Dec 2012
Application13/790,083Parent of this continuation · filed 8 Mar 2013
US 2015/0004699 A1Pre-grant publication · published 1 Jan 2015
US 8,883,857 B2Parent of this continuation
US 2014/0163045 A1Published application
US 9,622,988 B2This patent

From the US filing history. Foreign family members aren’t listed.

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