Substituted tricyclic compounds as FGFR inhibitors
AssigneesIncyte Holdings Corporation, Incyte Corporation
InventorsLiangxing Wu, Colin Zhang, Chunhong He, Liang Lu, Wenqing Yao
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Abstract
The present invention relates to tricyclic compounds, and pharmaceutical compositions of the same, that are inhibitors of one or more FGFR enzymes and are useful in the treatment of FGFR-associated diseases such as cancer.
Claims4
A compound which is 3-(2, 6-difluoro-3,5-dimethoxyphenyl)-1 -ethyl-8-(morpholin-4-ylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidin-2-one, or a pharmaceutically acceptable salt thereof.
A compound which is 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholin-4-ylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidin-2-one.
Dependencies are inferred from the claim text.