Paecilomyces variotii var. brunneolus GPP1101B, and preparation using same
AssigneeJS Bio Co., Ltd.
InventorsJong-Seog Kim, Wang-hyu Lee
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Abstract
The present invention relates to a paecilomyces variotii var. brunneolus GPP1101B (microorganism deposit number KCTC 119938BP) isolated during a ginseng fermentation process, and a preparation using the same. According to the present invention, remarkable anticancer, immune regulation, mutation inhibition and antibacterial effects are obtained by injecting the strain or the preparation into a ginseng extract or into a red ginseng extract.
Claims19
A method for manufacturing an immune active agent, the method comprising:
- cultivating a culture liquid by inputting into an extract liquid of ginseng or red ginseng a strain of paecilomyces variotii var. brunneolus GPP1101B (microorganism deposit number KCTC 11993BP).
A method for manufacturing an antibacterial active agent, the method comprising:
- cultivating a culture liquid by inputting into an extract liquid of ginseng or red ginseng a strain of paecilomyces variotii var. brunneolus GPP1101B (microorganism deposit number KCTC 11993BP).
A method for manufacturing an anti-tumor active agent, the method comprising:
- cultivating a culture liquid by inputting into an extract liquid of ginseng or red ginseng a strain of paecilomyces variotii var. brunneolus GPP1101B (microorganism deposit number KCTC 11993BP).
A method for manufacturing an anti-mutagen, the method comprising:
- cultivating a culture liquid by inputting into an extract liquid of ginseng or red ginseng a strain of paecilomyces variotii var. brunneolus GPP1101B (microorganism deposit number KCTC 11993BP).
A method for manufacturing a culture liquid, the method comprising:
- cultivating the culture liquid by inputting into an extract liquid of ginseng or red ginseng a strain of paecilomyces variotii var. brunneolus GPP1101B (microorganism deposit number KCTC 11993BP), wherein the strain of paecilomyces variotii var. brunneolus GPP1101B (microorganism deposit number KCTC 11993BP) is isolated during a ginseng fermentation process.
A method for preparing a culture filtrate, the method comprising:
- heating ginseng or red ginseng in water for a time period of about 12 to about 72 hours at a temperature of about 60° to about 100° C. to obtain a ginseng or red ginseng solution;
- filtering the ginseng or red ginseng solution to obtain an extract liquid;
- inputting a strain of paecilomyces variotii var. brunneolus GPP1101B (Microorganism Deposit No. KCTC 11993BP) into the extract liquid to obtain a culture liquid;
- cultivating the culture liquid for a time period of about 10 to about 60 days at a temperature of about 15° to about 35° C. using a cultivator to obtain an overgrown strain;
- and
- filtering the overgrown strain to obtain the culture filtrate.
Dependencies are inferred from the claim text.