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US 9,605,941 B2Granted
Lens-free tomographic imaging devices and methods
AssigneeThe Regents of the University of California
InventorsAydogan Ozcan, Serhan O. Isikman, Waheb Bishara
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Abstract
A lens-free system for the three-dimensional imaging of objects contained within a sample places a sample holder between an image sensor and an illumination source, with the sample-sensor distance being much smaller than the sample-illumination source distance. Holographic images are taken at different angles as well as different lateral jogs within a single angle and are reconstructed into a three dimensional image of objects within the sample. The system may be a hand held, portable unit.
Claims7
A hand held tomographic imager comprising:
- a hand held housing containing a sample holder configured to hold a sample with one or more objects therein;
- a plurality of partially coherent or coherent light sources disposed in the hand held housing, each of the plurality of light sources being coupled to respective waveguides that are mounted in a bridge wherein each respective waveguide is oriented at varying angles with respect to a first side of the sample;
- a microcontroller disposed in the hand held housing and operatively connected to the plurality of light sources, the microcontroller configured to selectively activate individual light sources;
- an electromagnetic actuator disposed in the hand held housing and configured to move the bridge and waveguides in substantially orthogonal directions;
- and
- a stationary image sensor disposed in the hand held housing on a second opposing side of the sample, wherein the waveguides are located a distance z1 from the sample and wherein the image sensor is located a distance z2 from the sample such that z2<<z1.
3 more elements
Dependencies are inferred from the claim text.