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US 9,603,937 B2Granted
Platform drug delivery system utilizing crystal engineering and theanine dissolution
AssigneeTheaprin Pharmaceuticals Inc.
InventorsHarry G. Brittain, Philip V. Felice
Life of this patent
Estimating the term…
Abstract
A platform drug delivery system and a method of improving the delivery of low solubility pharmaceuticals utilizing crystal engineering and Theanine dissolution resulting in enhanced bioactivity, dissolution rate, and solid state stability.
Claims3
A cocrystal of
- L-theanine;
- and
- doxorubicin,
- wherein said cocrystal is characterized as having an X-ray powder diffraction pattern with peaks (2θ) at 13.6, 18.2, 19.8, 22.0, 22.5, 25, and 38.2 degrees.
1 more element
A cocrystal of L-theanine and amoxicillin,
- wherein said cocrystal is characterized as having an X-ray powder diffraction pattern with peaks (2θ) at 12.1, 13.6, 15.0, 16.2, 17.0, 17.9, 19.3, 19.6, 20, 21.4, 22.0, 22.4, 22.7, 22.9, 23.5, 25, 25.6, 26.6, 28.6, and 29.4 degrees.
A cocrystal of sumatriptan and a coformer molecule selected from a group consisting of D-theanine and L-theanine,
- wherein said cocrystal is characterized as having an X-ray powder diffraction pattern with peaks (2θ) at 7.2, 9.4, 13.9, 14.5, 17.0, 17.4, 17.8, 18.6, 19.0, 19.6, 20.0, 20.3, 20.6, 21.1, 22.7, 24.4, 29.6, and 30.5 degrees.
Dependencies are inferred from the claim text.