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US 9,599,599 B2Granted
Measuring chemical properties of a sample fluid in dialysis systems
AssigneeFresenius Medical Care Holdings, Inc.
InventorsStephen R. Ash, Thomas A. Sullivan, David Carr, Michael James Beiriger
Life of this patent
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Abstract
In one aspect of the invention, a method includes determining an amount of carbon dioxide (CO2) in dialysate flowing through a dialysis system using a CO2 sensor associated with the dialysis system, determining, using a pH sensor associated with the dialysis system, a pH level of the dialysate, and calculating a level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 measured in the gas and the determined pH level of the dialysate.
Claims25
A method comprising:
- causing dialysate to flow into a chamber having a gas-permeable membrane and a material that is configured to alter an appearance of the material based at least in part on a pH level of the dialysate, wherein the chamber is removably attached to a hemodialysis machine having:
- a CO2 sensor,
- a pH sensor, and
- a dialyzer,
- determining an amount of carbon dioxide in the dialysate using the CO2 sensor
- determining a pH level of the dialysate using the pH sensor;
- calculating a level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 in the dialysate and the determined pH level of the dialysate;
- and
- causing bicarbonate to flow into the dialysate based at least in part on the calculated level of bicarbonate.
6 more elements
A method comprising
- causing dialysate to flow into a chamber having a gas-permeable membrane and a material that is configured to alter an appearance of the material based at least in part on a pH level of the dialysate, wherein the chamber is removably attached to a hemodialysis machine having:
- a CO2 sensor,
- a pH sensor, and
- a dialyzer, the chamber being positioned upstream of the dialyzer;
- determining an amount of carbon dioxide in the dialysate using the CO2 sensor
- determining a pH level of the dialysate using the pH sensor;
- calculating a level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 in the dialysate and the determined pH level of the dialysate;
- and
- determining a toxin removal efficiency based at least in part on the calculated bicarbonate level.
6 more elements
A method comprising:
- causing dialysate to flow into a first chamber positioned upstream from a dialyzer of a hemodialysis machine, the hemodialysis machine also having a CO2 sensor and a pH sensor, the chamber having a gas-permeable membrane and a material that is configured to alter an appearance of the material based at least in part on a pH level of the dialysate, wherein the first chamber is removably attached to the hemodialysis machine;
- determining a first amount of carbon dioxide in the dialysate using the CO2 sensor
- determining a first pH level of the dialysate using the pH sensor;
- calculating a first level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 in the dialysate and the determined pH level of the dialysate;
- causing dialysate to flow into a second chamber having a gas-permeable membrane and a material that is configured to alter an appearance of the material based at least in part on the pH level of the dialysate, wherein the second chamber is removably attached to the hemodialysis machine downstream from the dialyzer;
- determining an second amount of carbon dioxide in the dialysate using the CO2 sensor;
- determining a second pH level of the dialysate using the pH sensor;
- and
- calculating a second level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 in the dialysate and the determined pH level of the dialysate.
6 more elements
Dependencies are inferred from the claim text.