Immunoregulatory agents

A compound of the formula (I):

• or a pharmaceutically acceptable salt, hydrate or solvate thereof, wherein,
• the subscript n is 1;
• A is —C(O)—;
• B is —NH—;
• T is —CR3R4—;
• D is C(R5);
• E is C(R6);
• V is a bond;
• G is an optionally substituted quinolinyl;
• J1 is CH or C(R2), when R2 is attached to the ring vertex identified as J1;
• R1 and R2 are independently hydrogen, halogen, optionally substituted C1-C4 haloalkyl, optionally substituted C3-C6 cycloalkyl, optionally substituted 3- to 6-membered cycloheteroalkyl, optionally substituted phenyl, optionally substituted heteroaryl, optionally substituted C1-C4 alkyl, optionally substituted C1-C4 alkoxy, CN, SO2NH2, NHSO2CH3, NHSO2CF3, OCF3, SO2CH3, SO2CF3, or CONH2, and when R1 and R2 are on adjacent vertices of a phenyl ring they may be joined together to form a 5- or 6-membered cycloheteroalkyl ring having one or two ring vertices independently selected from O, N and S, wherein said cycloheteroalkyl ring is optionally substituted with from one to three members selected from fluoro and C1-C3 alkyl;
• R3 and R4 are independently hydrogen, optionally substituted C1-C6 alkyl, optionally substituted C1-C6 haloalkyl, fluorine, OH, CN, CO2H, C(O)NH2, N(R5a)2, optionally substituted —O—C1-C6 alkyl, —(CR5R5)m—OH, —(CR5R5)m—CO2H, —(CR5R5)m—C(O)NH2, —(CR5R5)m—C(O)NHR5a, —(CR5R5)mN(R5a)2, —NH(CR5R5)mCO2H or —NH(CR5R5)m—C(O)NH2;
• each R5 is independently H, F, OH, optionally substituted C1-C6 alkyl or optionally substituted —O—C1-C6 alkyl;
• each R5a is independently H, or optionally substituted C1-C6 alkyl;
• R6 is H, OH, F, optionally substituted C1-C6 alkyl, optionally substituted —O—C1-C6 alkyl, or —N(R5a)2;
• and each m is independently 1, 2, or 3.