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US 9,597,332 B2Granted
Sulfide alkyl compounds for HBV treatment
AssigneeNovira Therapeutics, Inc.
InventorsAustin Chen, Yalda Bravo, Nicholas Stock, Bijan Pedram, Jason Jacintho, Ryan C. Clark
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Abstract
The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.
Claims9
A compound of Formula IIIa:
- or a pharmaceutically acceptable salt, solvate, or N-oxide thereof;
- wherein
- each R1 is halo;
- R2 is halo;
- R3 is halo;
- and R4 is C3-7-cycloalkyl or (C1-6-alkyl)-(C3-7-cycloalkyl), each of which may be independently substituted with C(O)OH;
- or
- R4 is (C3-7-cycloalkyl)-C(O)R5, and R5 is C3-7-heterocycloalkyl.
5 more elements
Dependencies are inferred from the claim text.