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US 9,586,990 B2Granted
Enzymes for transforming ergopeptines and method therefor
AssigneeErber Aktiengesellschaft
InventorsGerd Schatzmayr, Eva-Maria Binder, Michaela Thamhesl, Dieter Moll
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Abstract
Enzymes for transforming, in particular hydrolytically cleaving, ergopeptines, which ergopeptines are α/β-hydrolases hydrolytically cleaving ergopeptines in the cyclol ring, for the transformation of ergopeptines, and method for producing ergopeptine-metabolizing enzymes.
Claims2
A method for hydrolysis of ergopeptine comprising contacting α/β-hydrolase with ergopeptine wherein the C3-N bond of the oxazolidine-4-one ring is cleaved to a primary metabolite, wherein the α/β-hydrolase has at least 96% sequence identity with SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.