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US 9,580,395 B2Granted
Compositions of dual thyrointegrin antagonists and use in vascular-associated disorders
AssigneeVascular Vision Pharmaceutical Co.
InventorShaker A. Mousa
Life of this patent
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Abstract
A dual thyrointegrin antagonist and a method for treating an angiogenesis-mediated disorder and/or a hyperthyroidism disorders by introducing the dual thyrointegrin antagonist into animals (e.g., mammals, human beings). The dual thyrointegrin antagonist includes a chemical structure having a thyroid hormone antagonist and αvβ3 integrin antagonist in the same molecule.
Claims5
A dual thyrointegrin antagonist having the chemical structure of
- wherein R is selected from the group consisting of hydrogen, methyl, ethyl, propyl, and isopropyl;
- wherein X is —(CH2)nNH2 such that n is 3, 4, or 5;
- wherein R1 is I, R2 is X, and R3 is I.
Dependencies are inferred from the claim text.