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US 9,579,399 B2Granted
Retinal OFF circuit-specific promoter
AssigneeFriedrich Miescher Institute for Biomedical Research
InventorsBotond Roska, Josephine Juettner
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Abstract
The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 200 bp having at least 70% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in cones and/or OFF bipolar cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
Claims9
An isolated nucleic acid molecule comprising the nucleic acid sequence of SEQ ID NO:
- 1, wherein said isolated nucleic acid molecule specifically directs expression of a gene in at least one cell selected from cones and OFF bipolar cells, when a nucleic acid sequence comprising the gene is operatively linked to said isolated nucleic acid molecule.
Dependencies are inferred from the claim text.