Treatment of headache disorders

A method for treatment of a headache disorder in a human subject, comprising:

• a) selecting at least one treatment area in the nasal cavity of the human subject, said treatment area being selected from a posterior part of the nasal cavity or an anterior part of the nasal cavity;
• b) providing a device comprising a stimulation member arranged for vibration stimulation of the selected treatment area, and at least one expansion member, said stimulation member being arranged to be expanded by the at least one expansion member, the expansion member being arranged at least partly within the stimulation member and provided with a channel having a plurality of openings arranged for fluid communication with the stimulation member, and wherein a bending stiffness of the expansion member in a first direction perpendicular to a longitudinal direction of the expansion member is different from a bending stiffness in a second direction perpendicular to said first direction and to the longitudinal direction of the expansion member;
• c) introducing the stimulation member into a nasal cavity of the human subject;
• d) expanding the stimulation member to a volume such that the stimulation member abuts against the tissue to exert a pressure on tissue of the selected treatment area;
• and
• e) bringing the stimulation member to vibrate in the nasal cavity to impart vibrations to the selected treatment area,
• wherein the vibrations are imparted:
• to a posterior part of the nasal cavity;
• to an anterior part of the nasal cavity;
• sequentially to a posterior and an anterior part of the nasal cavity;
• or
• simultaneously to a posterior and an anterior part of the nasal cavity.