North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
AssigneeZoetis Services LLC
InventorsJay Gregory Calvert, David Ewell Slade, Siao-Kun W. Welch
Life of this patent
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Abstract
The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, methods to make it and related polypeptides, polynucleotides, and various components. Vaccines comprising the genetically modified virus and polynucleotides and a diagnostic kit to distinguish between naturally infected and vaccinated animals are also provided.
Claims5
An isolated DNA polynucleotide molecule comprising a DNA sequence encoding an infectious RNA molecule encoding a North American PRRS virus, wherein said DNA sequence is selected from the group consisting of:
- (a) SEQ ID NO:
- 1, SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4, and SEQ ID NO:
- 6, or
- (b) the complement of any sequence in (a).
Dependencies are inferred from the claim text.