Inhibitors and methods of inhibiting bacterial and viral pathogens

A method for the treatment of a viral or bacterial infection or disease associated therewith wherein the viral infection is caused by a virus family selected from the group consisting of:

• Bunyaviridae, Poxviridae, Arenaviridae, Picornaviridae, Togaviridae, Flaviviridae, Filoviridae, Paramyxoviridae, Orthomyxoviridae and Retroviridae, comprising administering in a therapeutically effective amount to a mammal in need thereof, a compound of Formula II below or a pharmaceutically acceptable salt thereof:
• wherein X is selected from the group consisting of oxygen and NH;
• Y is selected from the group consisting of:
• —CH2—, —C(═O)—, —C(═S)— and —C(═NH)—;
• A is selected from the group consisting of:
• N and CR5;
• B is selected from the group consisting of:
• N and CR6;
• R1 is selected from the group consisting of:
• hydrogen and ethyl;
• R2 is selected from the group consisting of:
• hydrogen and chloro;
• R3 is selected from the group consisting of:
• hydrogen, methoxy, amino and hydroxyl;
• R4 is selected from the group consisting of:
• hydrogen, chloro and amino;
• R5 is selected from the group consisting of hydrogen and aminomethyl;
• and
• R6 is selected from the group consisting of hydrogen, amino and aminomethyl.