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US 9,550,878 B2Granted
Method for producing stabilized amorphous calcium carbonate
AssigneeAmorphical Ltd.
InventorsOren Meiron, Binyamin Ashkenazi
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Abstract
Provided is a method for preparing a stable amorphous calcium carbonate (ACC), which can be obtained either in suspension or as a powder. The method comprises stepwise combination of a soluble calcium salt, a soluble carbonate, a first and second stabilizer, and a water miscible organic solvent as described herein. The present invention further relates to stable ACC suspensions and dry powders produced by the method of the present invention.
Claims21
A method of preparing amorphous calcium carbonate (ACC), the method comprising:
- i) combining an aqueous solution comprising a soluble calcium salt and a first stabilizer with an aqueous solution comprising a soluble carbonate so as to form an ACC suspension;
- and
- ii) adding a water miscible organic solvent and a solution comprising a second stabilizer, substantially simultaneously or sequentially in any order, thereby obtaining a stabilized suspension of ACC;
- wherein the first stabilizer and the second stabilizer are the same or different;
- and
- wherein a total amount of first and second stabilizers constitutes up to about 12 weight % (wt %) of the stabilized ACC suspension, and the water miscible organic solvent constitutes at least about 5 wt % of the stabilized ACC suspension.
3 more elements
Dependencies are inferred from the claim text.