Medical apparatus and method for collecting biological samples
AssigneeThe Trustees of Columbia Universtity In the City of New York
InventorsAnjali Saqi, Keith Yeager
Life of this patent
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Abstract
A medical apparatus and method of preparing one or more cell blocks. The medical apparatus comprises at least one elongate tubular body having a proximal end and a distal end and a filter membrane disposed between the proximal end and a distal end of the elongate tubular body. The filter membrane, which can include alignment features and structural features to engage the tubular body, and/or cover, is sectionable. Additionally, in some embodiments a second elongate tubular body is provided which telescopingly receives at least a portion of the first elongate tubular body. In other embodiments, a support member is provided for engaging the filter membrane and positioning the filter membrane at a midpoint of the elongate tubular body during centrifuging.
Claims26
A medical apparatus comprising:
- a first elongate tubular body member having a proximal end and a distal end defining an interior space therebetween, and means for engaging a filter member assembly unit,
- a filter assembly unit comprising a bottom surface including a porous membrane and a base member having a body circumferentially surrounding the porous membrane and having upwardly extending sidewalls such that the bottom surface and upwardly extending sidewalls define a receptacle for collecting a biological sample, the filter assembly unit further including a structural reinforcement member for removably attaching to the engaging means of the first elongate tubular body member,
- wherein the base member consists essentially of paraffin material and the entire filter assembly unit is sliceable into sections suitable for mounting on a slide for microscopy.
A medical apparatus comprising:
- a first elongate tubular body member having a proximal end and a distal end defining an interior space therebetween, and means for engaging a filter member assembly unit;
- a second elongate tubular body member having a proximal end and a distal end defining an interior space therebetween sized to receive the first elongate tubular body, and
- a filter assembly comprising a unitary body having a bottom surface and upwardly extending sidewalls to define a receptacle suitable to hold a biological sample, and a structural reinforcement member for removably attaching the filter assembly to the engaging means of the first elongate tubular member,
- wherein the upwardly extending sidewalls consist essentially of paraffin material and the assembly is sliceable into sections suitable for mounting on a slide.
A filter assembly for preparing cells block comprising:
- a unitary body including a non-porous base member having an upwardly extending wall bordering a membrane having pores between about 0.4 μm to about 5 μm, the base member and porous membrane defining a receptacle suitable for collecting and processing a biological sample into a cell block, the unitary body further including at least one structural reinforcement member such that the filter assembly can removably attach to a tubular body member,
- wherein the non-porous base member consists essentially of paraffin material and the filter assembly sliceable into sections suitable for mounting on a slide for microscopy while holding a cell block.
Dependencies are inferred from the claim text.