Methods of diagnosing increased risk of developing MRSA
AssigneeWilliam Beaumont Hospital
InventorMatthew Sims
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Abstract
A method for diagnosing increased risk of developing Methicillin-resistant Staphylococcus aureus (MRSA) hospital-acquired (HA-MRSA) or community-acquired MRSA (CA-MRSA) which includes obtaining a biological sample from a subject, detecting in the sample a single nucleotide polymorphism (SNP) in the FAM129B gene at position 17 of SEQ ID NO 1, and comparing the nucleotide at position 17 of SEQ ID NO. 1 in the sample with the nucleotide at position 17 in SEQ ID NO. 1, wherein an adenine at position 17 of SEQ ID NO. 1 in the sample indicates an increased risk of developing MRSA or CA-MRSA in the subject.
Claims11
A method comprising the steps of:
- obtaining a biological sample from a human subject, wherein said biological sample comprises genomic DNA,
- analyzing the genomic DNA and detecting the presence of two copies of SEQ ID NO:
- 1 in the sample,
- predicting that the subject has an increased risk of developing a MRSA infection, and
- administering to the human subject anti MRSA antibiotics.
A method comprising the steps of:
- obtaining a biological sample from a human subject, wherein said biological sample comprises genomic DNA,
- analyzing the genomic DNA and detecting the presence of two copies of SEQ ID NO:
- 2 in the sample,
- predicting that the subject has a decreased risk of developing a MRSA infection, and
- treating the subject with incision and drainage in the absence of antibiotics.
A method comprising the steps of:
- obtaining a biological sample from a human subject, wherein said biological sample comprises genomic DNA,
- analyzing the genomic DNA and detecting the presence of two copies of SEQ ID NO:
- 2 in the sample,
- predicting that the subject has a decreased risk of developing a MRSA infection, and
- treating the subject with incision and drainage and a common antibiotic.
Dependencies are inferred from the claim text.