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US 9,540,670 B2Granted
Mutated T7 RNA Polymerases
AssigneesBiomerieux, Commissariat A L'energie Atomique Et Aux Energies Alternatives
InventorsJean-Claude Boulain, Janie Dassa, Frédéric Ducancel, Bruno H. Muller, Alain Troesch, Laurent Mesta
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Abstract
The present invention pertains to a mutated T7 RNA polymerase and its use, the T7 RNA polymerase being mutated at position 744, the glutamine (Q) being replaced by an amino acid selected from arginine (Q744R), leucine (Q744L) or proline (Q744P).
Claims12
A T7 RNA polymerase comprising the amino acid sequence of SEQ ID NO:
- 16 that is mutated at position 744, wherein the glutamine (Q) at position 744 is replaced by an amino acid selected from arginine (Q744R), leucine (Q744L) or proline (Q744P).
Dependencies are inferred from the claim text.