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US 9,540,609 B2Granted
Lactobacillus rhamnosus food grade bacteria
OwnerJeremy Burton, Marc Monaches +4inventors
InventorsJeremy Burton, Marc Monaches, Gregor Reid, Tamara Smokvina, Johan Van Hylckama Vlieg, Jordan Bisanz
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Abstract
The present invention relates to food-grade bacteria strain being capable of removing mercury from an aqueous environment.
Claims15
A method for providing a genetically modified strain of Lactobacillus rhamnosus, comprising:
- providing the Lactobacillus rhamnosus strain DN 116-0060 (deposited with the Collection Nationale de Cultures de Microorganisms (CNCM) under number I-4719);
- and
- genetically modifying the Lactobacillus rhamnosus strain DN 116-0060 by at least one of mutagenesis and genetic transformation to thereby provide the genetically modified strain of Lactobacillus rhamnosus.
A method for obtaining a cell fraction lysate comprising:
- a) providing the Lactobacillus rhamnosus strain DN 116-0060 (deposited with the Collection Nationale de Cultures de Microorganisms (CNCM) under number I-4719),
- b) genetically modifying the Lactobacillus rhamnosus strain DN 116-0060 by at least one of mutagenesis and genetic transformation to thereby provide a genetically modified strain of Lactobacillus rhamnosus, and
- c) recovering the cell lysate from the culture;
- wherein the cell lysate is capable of removing mercury from an aqueous environment.
1 more element
A composition for administration to a subject, comprising:
- Lactobacillus rhamnosus strain DN 116-0060 (deposited with the Collection Nationale de Cultures de Microorganisms (CNCM) under number I-4719) or a cell lysate thereof;
- and
- an effective amount of a protective agent that protects the Lactobacillus rhamnosus strain DN 116-0060, or cell lysate thereof, in the composition from inactivation during administration to a subject.
A composition comprising:
- yogurt;
- and
- Lactobacillus rhamnosus strain DN 116-0060 (deposited with the Collection Nationale de Cultures de Microorganisms (CNCM) under number I-4719) or a cell lysate thereof;
- wherein the Lactobacillus rhamnosus strain DN 116-0060 or cell lysate thereof is dispersed throughout the yogurt.
1 more element
Dependencies are inferred from the claim text.