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US 9,540,548 B1Granted
Adhesive compositions and related methods
AssigneeXcede Technologies, Inc.
InventorsDaniel Grant Ericson, Kyle Robert Brandy
Life of this patent
Estimating the term…
Abstract
Adhesive compositions and patches, and associated systems, kits, and methods, are generally described. Certain of the adhesive compositions and patches can be used to treat tissues (e.g., in hemostatic or other tissue treatment applications), according to certain embodiments.
Claims23
A method of forming an adhesive matrix, comprising:
- establishing a mixture comprising a non-aqueous liquid, a first polyacrylic acid crosslinked with pentaerythritol and/or allyl sucrose, and a second polyacrylic acid crosslinked with divinyl glycol on a substrate, wherein the amount of water in the mixture is less than or equal to about 2 wt. %;
- applying a non-aqueous polar solvent to the mixture on the substrate, wherein the non-aqueous polar solvent contains at least one of methanol, ethanol, propanol, and butanol;
- and
- allowing at least a portion of the non-aqueous liquid and the non-aqueous polar solvent to evaporate to produce the adhesive matrix,
- wherein, after the evaporation, the sum of the amount of the non-aqueous liquid and the non-aqueous polar solvent in the adhesive matrix is between about 0.001 wt % and about 3 wt %.
2 more elements
A tissue adhesive composite, comprising:
- a tissue adhesive film positioned on at least a portion of a substrate,
- wherein the tissue adhesive film comprises:
- a first polyacrylic acid crosslinked with pentaerythritol and/or allyl sucrose;
- a second polyacrylic acid crosslinked with divinyl glycol;
- and
- a liquid comprising at least one of methanol, ethanol, propanol and butanol;
- wherein:
- greater than or equal to about 90 wt % of the tissue adhesive film is made up of polyacrylic acid, and
- less than about 8 wt % of the tissue adhesive film is made up of the liquid.
6 more elements
Dependencies are inferred from the claim text.