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US 9,540,425 B2Granted
Vaccines against pregnancy-associated malaria
AssigneeInstitut De Recherche Pour Le Developpement (Ird)
InventorsNicaise Tuikue Ndam, Philippe Deloron, Sedami Ursula Alix Carine Gnidéhou, Mickaël Quiviger, Pascal Bigey, Daniel Scherman
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Abstract
The present invention relates to specific regions of the N-terminal portion of the VAR2CSA protein and to the use of such specific regions in the prevention of pregnancy-associated malaria. The invention also provides immunogenic compositions and vaccines that are useful for preventing malaria in pregnant women.
Claims10
A fusion protein consisting of an isolated polypeptide fused to a fusion partner, wherein the polypeptide consists of the amino acid sequent set forth in SEQ ID NO:
- 1 or the amino acid sequence set forth in SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.