Thienopyrimidines

A compound of formula (I):

• in which:
• R1 represents a group selected from:
• —C(═O)O—R3, —C(═O)N(H)R3, and —C(═O)NR3R4;
• R2a represents a hydrogen atom;
• R2b represents a hydrogen atom;
• R2c represents a hydrogen atom;
• R2d represents a hydrogen atom or a group selected from:
• C1-C3-alkyl-, C1-C3-alkoxy-, halo-, —N(H)R5, —NR5R4;
• R3 represents a hydrogen atom or a group selected from:
• C1-C6-alkyl-, C2-C6-alkynyl-, C3-C7-cycloalkyl-, —(CH2)q—(C3-C7-cycloalkyl), —(CH2)q—O—(C3-C7-cycloalkyl),
• 3- to 10-membered heterocycloalkyl-, —(CH2)q-(3- to 10-membered heterocycloalkyl), —(CH2)q—O-(3- to 10-membered heterocycoalkyl),
• aryl-, —(CH2)q-aryl, —(CH2)q—O-aryl, heteroaryl-, —(CH2)q-heteroaryl, —(CH2)q—O-heteroaryl;
• said group being optionally substituted, one or more times, identically or differently, with a substituent selected from:
• halo-, hydroxyl-, oxo (═O), cyano-, C1-C6-alkyl-, C2-C6-alkynyl-,
• halo-C1-C6-alkyl-, C1-C6-alkoxy-, —N(H)R5, —NR5R6, —R4—S(═O)2—;
• or
• when two substituents are present ortho to each other on an aryl- or heteroaryl-ring, said two substituents together form a bridge:
• *O(CH2)pO*, *NH(C(═O))NH*, wherein * represents the point of attachment to said aryl- or heteroaryl-ring;
• R4 represents a
• C1-C6-alkyl-group
• or
• NR3R4 together
• represent a 3- to 10-membered heterocycloalkyl group, which is optionally substituted, one or more times, identically or differently, with —CN, —OH, C1-C6-alkyl-, R6R7N—, R6R7N—C1-C6-alkyl- or —C(═O)NR6R7;
• R5 represents a hydrogen atom or a C1-C6-alkyl-group;
• R6 represents a hydrogen atom or a C1-C6-alkyl-group;
• R7 represents a hydrogen atom or a C1-C6-alkyl-group;
• or
• NR6R7 together represent a 3- to 10-membered heterocycloalkyl group;
• p represents 1;
• q represents an integer of 1, 2 or 3;
• or a tautomer, an N-oxide, a hydrate, a solvate, or a salt thereof.