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US 9,540,355 B2Granted
Irciniastatin analogues
AssigneeThe Trustees of the University of Pennsylvania
InventorsAmos B. Smith, III, Chihui An, Adam T. Hoye
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Abstract
The present invention is directed to irciniastatin analogs. Uses of these analogs also described.
Claims21
A compound of Formula I, or a stereoisomer thereof,
- wherein
- R1 is hydrogen;
- and
- R2 is halogen, O—C(O)phenyl, O—C(O)C1-6alkyl, or C1-6 alkyl, or wherein R1 and R2 together form ═CR3R4 or ═NR5 wherein R3 and R4 are independently hydrogen or C1-6 alkyl, and R5 is O—C1-6 alkyl;
- or a pharmaceutically acceptable salt thereof.
2 more elements
Dependencies are inferred from the claim text.