(−)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt, its method of production and use
AssigneeAllergan, Inc.
InventorsGyorgy F. Ambrus, Katherine C. Kurjan, Jacopo Zanon, Giovanna Libralon, Carla De Faveri
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Abstract
The present invention is directed to (−)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt, a pharmaceutical composition comprising said salt, a process for making said salt, and the use of said salt in the treatment of pain.
Claims11
A salt that is (−)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt in crystalline form and having an X-ray powder diffraction spectrum with peaks expressed in degrees (2θ) at approximately 7.61, 7.89, 12.97, 13.50, 15.13, 15.19, 15.38, 16.23, 16.71, 16.83, 17.05, 19.76, 20.14, 20.43, 20.76, 21.00, 22.77, 22.86, 23.07, 23.66, 24.58, 24.90, 25.11, 25.35, 25.63, 25.83, 26.33, 27.09, 28.08, 30.71, 31.02, 31.72, 33.00 and 34.15.
Dependencies are inferred from the claim text.