Proteoglycan-containing microneedle array
AssigneeCosmed Pharmaceutical Co., Ltd.
InventorsYing-shu Quan, Fumio Kamiyama, Takao Taki, Kazuyoshi Kawai, Tadayoshi Takemoto, Takuya Hamabuchi, Kazuhide Ohta
Life of this patent
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Abstract
A microneedle array is provided which has (1) the strength to withstand insertion into the skin surface layer and/or stratum corneum, (2) the fineness and flexibility to cause no pain or bleeding in the skin surface layer and/or stratum corneum at the insertion site of the microneedles, and (3) solubility or biodegradability of the microneedle portions under the skin. The microneedle array is produced by forming microneedles using proteoglycan as a base material.
Claims6
A microneedle array comprising one or more microneedles formed on a surface of a substrate, the microneedles comprising proteoglycan as a base material, wherein:
- each of the microneedles is a solid needle,
- each of the microneedles has a konide-like shape or a circular truncated cone shape,
- the proteoglycan content in each of the microneedles is 50, to 100, wt.%,
- the proteoglycan is distributed homogeneously in the solid needles, and
- the proteoglycan is chondroitin sulfate proteoglycan.
Dependencies are inferred from the claim text.