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US 9,539,365 B2Granted
Fiber wadding for filling bone defects
AssigneesOrthorebirth Co., Ltd., Nagoya Institute of Technology
InventorsToshihiro Kasuga, Akiko Obata, Kie Fujikura, Yoshio Ota, Xianfeng Yao
Life of this patent
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Abstract
A fiber wadding for filling bone defects having a flocculent three-dimensional structure is disclosed. The fiber wadding includes a plurality of fibers that contain a biodegradable resin as a principal component and a siloxane. Outside diameter of the plurality of fibers of the wadding is from about 0.05 μm to about 30 μm. Bulk density of the fiber wadding is about 0.005-0.3 g/cm3.
Claims12
A fiber wadding for filling bone defects, comprising:
- a plurality of biodegradable fibers produced by using an electrospinning apparatus having a collector filled with ethanol, wherein electrospun fibers emitted from a nozzle of the electrospinning apparatus enter into the ethanol of the collector, and the fiber sink in the ethanol and are deposited in the collector,
- wherein the plurality of biodegradable fibers are entangled with each other to form a flocculent three dimensional structure having a bulk density from about 0.01 g/cm3 to about 0.1 g/cm 3, as measured in accordance with JIS L 1097,
- wherein the plurality of biodegradable fibers comprise a biodegradable resin and a Si-releasable calcium compound.
A fiber wadding for filling bone defects, comprising:
- a plurality of biodegradable fibers produced by using an electrospinning apparatus having a collector filled with ethanol, wherein electrospun fibers emitted from a nozzle of the electrospinning apparatus enter into the ethanol of the collector, and the fibers sink in the ethanol and are deposited in the collector,
- wherein the plurality of biodegradable fibers comprise a biodegradable resin and a bone formation element, and
- wherein the plurality of biodegradable fibers are entangled with each other to form a flocculent three dimensional structure having a bulk density from about 0.01 g/cm3 to about 0.1 g/cm 3, compressibility from about 10% to about 55%, and compression recovery from about 5% to about 76%, as measured in accordance with JIS L 1097.
Dependencies are inferred from the claim text.