Small molecule cancer treatments that cause necrosis in cancer cells but do not affect normal cells
AssigneeThe Research Foundation for The State University of New York
InventorsMatthew R. Pincus, Josef Michl, Ehsan Sarafraz-Yazdi
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Abstract
A method of treating cancer in a subject, including: providing a subject having a plurality of cancer cells; and administering to the subject, a therapeutically effective amount of a composition including: an HDM-2 binding component; and a membrane resident component, the membrane resident component bound to the HDM-2 binding component. Also provided are a method of selectively necrosing cancer cells, a method of causing membranolysis in cancer cells, and a cancer treatment composition.
Claims3
A method of treating cancer in a subject, said method comprising:
- providing a subject having a plurality of cancer cells;
- and
- administering to the subject, a therapeutically effective amount of a composition including:
- an HDM-2 binding component comprising:
- and
- a membrane resident component comprising:
- said membrane resident component bound to said HDM-2 binding component.
Dependencies are inferred from the claim text.