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US 9,539,325 B2Granted
Combination therapy for treating breast cancer
AssigneeGenzyme Corporation
InventorsJay Harper, Scott Lonning, Frank Hsu
Life of this patent
Estimating the term…
Abstract
The invention provides compositions and methods for treating breast cancer. Specifically, the invention relates to administering a Transforming Growth Factor beta (TGFβ) antagonist in combination with capecitabine and ixabepilone to treat breast cancer.
Claims16
A pharmaceutical composition to treat a breast cancer in a subject, comprising:
- a therapeutically effective amount of a Transforming Growth Factor beta (TGFβ) antagonist, capecitabine, and ixabepilone, wherein said TGFβ antagonist is present in an amount effective to enhance the efficacy of capecitabine and ixabepilone to treat said breast cancer.
A kit to treat a breast cancer in a subject, comprising:
- a therapeutically effective amount of a Transforming Growth Factor beta (TGFβ) antagonist, capecitabine, and ixabepilone, wherein said TGFβ antagonist is present in an amount effective to enhance the efficacy of capecitabine and ixabepilone to treat said breast cancer.
Dependencies are inferred from the claim text.