Immunomodulation using placental stem cells
AssigneeAnthrogenesis Corporation
InventorsCasper Paludan, James W. Edinger, Ryhor Harbacheuski, RoseAnn Murray, Robert J. Hariri
Life of this patent
Estimating the term…
Abstract
The present invention provides methods of immunomodulation using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of immunomodulation, and compositions comprising such cells and cell populations.
Claims19
A method of treating graft-versus-host disease in a subject comprising administering a therapeutically effective amount of placental stem cells to the subject, wherein said placental stem cells suppress T cell proliferation stimulated by Epstein-Barr virus antigen-presenting B cells;
- and
- wherein at least 80% of said placental stem cells express CD200.
Dependencies are inferred from the claim text.