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US 9,539,277 B2Granted
Defibrotide for use in prophylaxis and/or treatment of graft versus host disease (GVHD)
AssigneeGentium S.R.L.
InventorMassimo Iacobelli
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Abstract
Defibrotide for use in prophylaxis and/or treatment of Graft versus Host Disease (GVHD) in humans is disclosed, preferably in hematopoietic stem cell transplantation (HSCT), more preferably allogeneic hematopoietic stem cell transplantation. Graft versus Host Disease of the invention (GVHD) can be acute aGVHD and/or chronic cGVHD, preferably acute.
Claims14
A method of preventing or alleviating graft versus host disease (GVHD) comprising identifying a patient at risk of developing GVHD, and administering to the patient an amount of defibrotide sufficient to reduce the occurrence or severity of GVHD.
Dependencies are inferred from the claim text.