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US 9,539,203 B2Granted
Pharmaceutical composition comprising a Vitamin E derivative and a cell death marker
AssigneeUCL Business PLC
InventorsFrancesca Cordeiro, Stephen Moss
Life of this patent
Estimating the term…
Abstract
The invention relates to a carrier for delivering agents to the posterior region of the eye, the carrier comprising a Vitamin E derivative, especially tocopherol. The carrier may also comprise a cell death marker, such as an annexin.
Claims15
A pharmaceutical composition, comprising:
- a combination of a Vitamin E derivative and a cell death marker, wherein the cell death marker is annexin V or a functional fragment or derivative thereof that binds reversibly to cellular membranes in the presence of cations.
A pharmaceutical composition comprising a Vitamin E derivative;
- and a cell death marker, wherein the cell death marker is an annexin or functional fragment or derivative thereof that binds reversibly to cellular membranes in the presence of cations and wherein the Vitamin E derivative is D-[alpha]-tocopherylsuccinate esterified to polyethyleneglycol 1000.
Dependencies are inferred from the claim text.