Compositions comprising a SIRT6 activator and a DNA repair enzyme
AssigneeELC Management LLC
InventorsNadine Pernodet, Kelly Dong, Edward Pelle
Life of this patent
Estimating the term…
Abstract
Compositions of the invention comprise 8-oxoguanine glycosylase (OGG1) and SIRT6 activating peptide G-A-G-V-S-A-E-NH2. Compositions of the invention exhibit anti-aging effects by promoting the repair of skin cell DNA and/or by protecting skin cell DNA from UV damage.
Claims2
A method for repairing DNA fragmentation due to UVB exposure in skin cells in need of such treatment, the method comprising the step of topically applying a composition that comprises 0.0001% to 1% of a SIRT6 activating peptide and 0.0001%-0.05% of 8-Oxoguanine glycosylase, by weight of the composition, wherein the SIRT 6 activating peptide is
- (SEQ ID No. 1)
- G-A-G-V-S-A-E-NH2
- Gly-Ala-Gly-Val-Ser-Ala-Glu-NH2.
A composition that comprises 0.0001% to 1% of a SIRT6 activating peptide and 0.0001%-0.05% of 8-Oxoguanine glycosylase, by weight of the composition, wherein the SIRT 6 activating peptide is
- (SEQ ID No. 1)
- G-A-G-V-S-A-E-NH2
- Gly-Ala-Gly-Val-Ser-Ala-Glu-NH2.
Dependencies are inferred from the claim text.