Method of ophthalmic surgery and kit therefor

A method of micro-incision ophthalmic surgery, comprising, in the order mentioned, the steps of:

• (1) injecting a first viscoelastic substance, which is an aqueous solution containing hyaluronic acid or a salt thereof, wherein a concentration of hyaluronic acid or a salt thereof in the aqueous solution is about 1% (w/v) in which hyaluronic acid or a salt thereof has a weight-average molecular weight in the range of from 600,000 to 1,200,000, through an incision site which is to the side of the cornea filling a part of the anterior chamber opposite the incision site with discharging aqueous humor and without coating the anterior capsule:
• (2) injecting a second viscoelastic substance, which is an aqueous solution containing hyaluronic acid or a salt thereof, wherein a concentration of hyaluronic acid or a salt thereof in the aqueous solution is about 1% (w/v) in which hyaluronic acid or a salt thereof has a weight-average molecular weight in the range of from 1,900,000 to 3,900,000 and which has higher surface tension than that of the first viscoelastic substance, through the incision site into a part of the anterior chamber at the same side as the incision site and such that the second substance contacts the incision site;
• and
• (3) injecting a third viscoelastic substance, which is an aqueous solution containing hyaluronic acid or a salt thereof, wherein a concentration of hyaluronic acid or a salt thereof in the aqueous solution is about 1% (w/v) in which hyaluronic acid or a salt thereof has a weight-average molecular weight in the range of from 600,000 to 1,200,000 and which has lower surface tension than that of the second viscoelastic substance, through the incision site into the part of the anterior chamber which is filled with the first viscoelastic substance until the incision site is sealed with the already injected second viscoelastic substance.