System and method of evaluating a subject with an ingestible capsule

A non-transitory computer-readable medium encoded with computer-executable instructions for performing a method comprising:

• receiving measurements related to a gastrointestinal tract parameter of a subject recorded by at least one sensor, wherein said sensor is selected from a pH sensor, a pressure sensor and a temperature sensor, on a capsule ingested by said subject;
• conditioning said measurements to provide sensor data, the sensor data including at least a pH data, a pressure data and/or a temperature data;
• establishing a baseline body temperature by determining an average body temperature of the temperature data;
• defining a physical swallow of the capsule as a pH minimum located between a beginning of the pH data and a boundary point, the boundary point being a maximum pH value located in pH data after a potential stomach entry point, the potential stomach entry point being a pH data point corresponding to a temperature data point at or above the baseline body temperature;
• plotting said sensor data on a display as a function of time to produce a plot representing the gastrointestinal tract parameter;
• providing a suggested marker on said plot at a location identifying a gastrointestinal transition time;
• receiving, via an input device, input from a user in response to a query regarding the location of the suggested marker on said plot;
• setting the suggested marker on said plot at a location as a function of said input;
• and
• determining a capsule transit time in said gastrointestinal tract as a function of the location of said suggested marker as set on said plot.

A system for analyzing measurements obtained from the gastrointestinal tract of a subject comprising:

• an ingestible capsule having at least one sensor, wherein said at least one sensor is selected from a pH sensor, a pressure sensor and a temperature sensor, for recording measurements as said capsule passes through at least a portion of said subject's gastrointestinal tract, said measurements are related to a parameter of the gastrointestinal tract;
• a receiver adapted to receive said measurements when transmitted from said capsule;
• a processor adapted to communicate with said receiver;
• a display in communication with said processor;
• an input device in communication with said processor;
• said processor programmed to:
• receive said measurements;
• condition said measurements to provide sensor data, the sensor data including at least a pH data, a pressure data and/or a temperature data;
• establish a baseline body temperature by determining an average body temperature of the temperature data;
• define a physical swallow of the capsule as a pH minimum located between a beginning of the pH data and a boundary point, the boundary point being a maximum pH value located in pH data after a potential stomach entry point, the potential stomach entry point being a pH data point corresponding to a temperature data point at or above the baseline body temperature;
• plot said sensor data on said display as a function of time to produce a plot representing the gastrointestinal tract parameter;
• provide a suggested marker on said plot at a location identifying a gastrointestinal transition time;
• receive input from said input device in response to a query regarding the location of the suggested marker on said plot;
• set the suggested marker on said plot at a location as a function of said input;
• and
• determine a capsule transit time in said gastrointestinal tract as a function of the location of said suggested marker as set on said plot.