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US 9,538,782 B2Granted
Inhibition of sensory irritation during consumption of smokeless tobacco products using a combinatorial approach
AssigneeAltria Client Services LLC
InventorsGerd Kobal, Douglas Oliveri, Peter Reeh, Maria Gogova
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Abstract
Combinations of compounds utilized to minimize the sensory irritating character of non-smokeable tobacco products or non-smokeable products containing tobacco extracts or materials derived from tobacco.
Claims18
A tobacco product comprising:
- a smokeless tobacco product selected from the list consisting of chewing tobacco, moist smokeless tobacco and dry snuff;
- at least two active ingredients;
- wherein the first active ingredient is an antagonist of a nicotinic acetylcholine receptor and the second active ingredient is an antagonist of a TRP ion channel;
- and
- wherein the tobacco product does not comprise mercaptan or curcumin.
2 more elements
A method of making a tobacco product comprising:
- combining a smokeless tobacco product with at least a first and second active ingredient;
- wherein the first active ingredient is an antagonist of a nicotinic acetylcholine receptor and the second active ingredient is an antagonist of a TRP ion channel;
- wherein the first and second active ingredients are present in an amount effective to reduce or eliminate sensory irritation arising during use of the product;
- and
- wherein the tobacco product does not comprise mercaptan or curcumin.
2 more elements
Dependencies are inferred from the claim text.